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Zhengming Yan Selected Research

nirogacestat

6/2014Comparison of dynamic contrast-enhanced MR, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF-03084014 and sunitinib.
3/2013Synergistic effect of the γ-secretase inhibitor PF-03084014 and docetaxel in breast cancer models.
9/2012Biomarker and pharmacologic evaluation of the γ-secretase inhibitor PF-03084014 in breast cancer models.

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Zhengming Yan Research Topics

Disease

12Neoplasms (Cancer)
08/2022 - 04/2008
3Breast Neoplasms (Breast Cancer)
08/2022 - 09/2012
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2022
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018
1Hematologic Neoplasms (Hematological Malignancy)
06/2017
1Triple Negative Breast Neoplasms
03/2013
1Tics (Tic)
03/2013
1Lymphoma (Lymphomas)
01/2013
1Burkitt Lymphoma (Burkitt's Lymphoma)
01/2013
1Neoplasm Metastasis (Metastasis)
09/2012
1Disease Progression
01/2009
1Retinoblastoma (Glioblastoma, Retinal)
04/2008

Drug/Important Bio-Agent (IBA)

4Docetaxel (Taxotere)FDA Link
03/2013 - 01/2009
3Amyloid Precursor Protein Secretases (beta-Secretase)IBA
06/2014 - 09/2012
3nirogacestatIBA
06/2014 - 09/2012
2palbociclibIBA
08/2022 - 01/2009
1Hormones (Hormone)IBA
08/2022
1Cyclin-Dependent Kinase 4IBA
08/2022
1ErbB Receptors (EGF Receptor)IBA
08/2022
1A-Form DNA (A-DNA)IBA
01/2022
1fimepinostatIBA
01/2021
1CUDC-907IBA
01/2021
1Gemtuzumab (Mylotarg)FDA Link
01/2018
1Immunoconjugates (Immunoconjugate)IBA
01/2018
1Immunoglobulin G (IgG)IBA
06/2017
1Chemokine ReceptorsIBA
06/2017
1Sunitinib (Sutent)FDA Link
06/2014
1SurvivinIBA
03/2013
1AntigensIBA
01/2013
1Indicators and Reagents (Reagents)IBA
01/2013
1LuciferasesIBA
01/2013
1Sirolimus (Rapamycin)FDA Link
01/2013
1Tissue ExtractsIBA
01/2013
1alovudineIBA
01/2013
1Biomarkers (Surrogate Marker)IBA
09/2012
1Messenger RNA (mRNA)IBA
09/2012
1ThymidineIBA
03/2012
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
11/2010
1Cadherins (E-Cadherin)IBA
11/2010
1Monoclonal AntibodiesIBA
11/2010
1PF-03732010 monoclonal antibodyIBA
11/2010
1PF 00477736IBA
07/2009
1Capsules (Microcapsules)IBA
01/2009
1Bevacizumab (Avastin)FDA Link
01/2009
1Antineoplastic Agents (Antineoplastics)IBA
01/2009
1AG-012986IBA
04/2008

Therapy/Procedure

8Therapeutics
08/2022 - 01/2009
2Drug Therapy (Chemotherapy)
01/2022 - 01/2013
2Aftercare (After-Treatment)
06/2014 - 09/2012
1Induction Chemotherapy
01/2018
1Microbubbles
06/2014